Rolesets - abrogate

abrogate

abrogate.01 - block a biological process or function

ABROGATE-V NOTES: Created for Bio-AMR annotations. No VN, FN class.

Aliases:

abrogate (v.)
abrogation (n.)

Roles:

ARG0-PAG: intentional agent of abrogation (e.g. scientist)
ARG1-PPT: thing abrogated, blocked
ARG2-MNR: instrument

abrogate-v: active use

Cleavage site mutations in the encephalomyocarditis virus P3 regionARG0
lethallyARGM-MNR
abrogaterel
the normal processing cascadeARG1
.

abrogate-v: with agent

By treating cells with RUNX2 siRNAARGM-MNR
,
weARG0
abrogatedrel
the Wip1 - dependent activation of Bax expression and the cells sensitization to cis - platinARG1
.

abrogation-n

Abrogationrel
of TGF beta signalingARG1
in mammary carcinomasARGM-LOC
recruits Gr-1+CD11b+ myeloid cells that promote metastasis .