Rolesets - denature

denature

denature.01 - modify the molecular structure (of a protein or other biological macromolecule)

For Bio-AMR annotations.

Aliases:

denature (v.)
denaturation (n.)

Roles:

ARG0-PAG: intentional agent of denaturation (e.g. scientist)
ARG1-PPT: thing denatured
ARG2-GOL: end state
ARG3-DIR: start state
ARG4-MNR: instrument, denaturant

example with agent

WeARG0
denaturedrel
the RNA / primer combinationsARG1
, assembled the reactions and incubated for coupled RT - PCR .

example with instrument

In Anfinsen 's experiment ,
RNAseARG1
was
denaturedrel
with
urea and β - mercaptoethanolARG4
.

example with start state and end state

The target DNAARG1
is
denaturedrel
from
dsDNAARG3
to
ssDNAARG2
by heating to about 95 ° C .