downregulate
downregulate.01 - reduce a cellular response to a molecular stimulus
DOWNREGULATE-V NOTES: Created for Bio-AMR annotations.Aliases:
downregulate (v.)
downregulation (n.)
downregulation (n.)
Roles:
ARG0-PAG: intentional agent of downregulation (e.g. scientist)
ARG1-PPT: thing downregulated (e.g. protein or another molecule)
ARG2-MNR: instrument (e.g. enzyme)
ARG1-PPT: thing downregulated (e.g. protein or another molecule)
ARG2-MNR: instrument (e.g. enzyme)
downregulate-v: example with instrument
The two - handed E box binding zinc finger protein SIP1ARG2
downregulatesrel
E - cadherinARG1
and induces invasion .downregulate-v: with intentional agent
In this studyARGM-LOC
, weARG0
downregulatedrel
miR-34s in human mesothelial cellsARG1
to investigate the cellular effect of miR-34 knockdownARGM-PRP
.downregulation-n
Some receptor agonists may cause
downregulationrel
of their respective receptor(s )ARG1
,