Rolesets - dysregulate

dysregulate

dysregulate.01 - impair a physiological regulatory mechanism

DYSREGULATE-V NOTES: Created for Bio-AMR annotations.

Aliases:

dysregulate (v.)
dysregulation (n.)

Roles:

ARG0-PAG: agent of dysregulation (e.g. scientist)
ARG1-PPT: thing dysregulated (e.g. signaling)
ARG2-MNR: instrument (e.g. protein, drug)

dysregulate-v: with instrument

E1A expressionARG2
dysregulatesrel
IL-8 productionARG1
and suppresses IL-6 production by lung epithelial cells .

dysregulate-v: with all arguments

To determine whether a more physiological level of RipA could be converted to a lethal autolysinARGM-PRP
,
weARG0
dysregulatedrel
RipA activityARG1
through the use of the beta - lactam antibiotic meropenemARG2
.

dysregulation-n

Addiction is presented as a cycle of
spirallingARGM-ADJ
dysregulationrel
of brain reward systemsARG1