Rolesets - heterodimerize

heterodimerize

heterodimerize.01 - form a dimer from two different monomers

For Bio-AMR annotations.

Aliases:

heterodimerize (v.)
heterodimerization (n.)

Roles:

ARG0-PAG: agent of heterodimerization
ARG1-PPT: monomer 1
ARG2-PPT: monomer 2
ARG3-PRD: result, heterodimer

monomers 1 and 2

To rule out the possibility that
these mutantsARG1
were incapable of forming an active site ,
weARG0
heterodimerizedrel
each of them with
the caspase-8 activator c - FLIPLARG2
.

example with result

Oppmann and colleagues identified
an IL-6 / IL-12 - related subunit , p19ARG2
, with which
p40ARG1
heterodimerizesrel
to form
the cytokine IL-23ARG3
( 36 ) .