Rolesets - phosphorylate

phosphorylate

phosphorylate.01 - introduce a phosphate group into an organic compound

PHOSPHORYLATE-V NOTES: Created for Bio-AMR annotations.

Aliases:

phosphorylate (v.)
phosphorylation (n.)

Roles:

ARG0-PAG: intentional agent of phosphorylation (e.g. person)
ARG1-PPT: thing phosphorylated (e.g. protein or another organic molecule)
ARG2-MNR: instrument (e.g. enzyme)
ARG3-PRD: product of phosphorylation (e.g. protein or another organic molecule)

phosphorylate-v: passivized, with product of the reaction

What is most striking in our proteomic analysis of PHF is the abundance of
MAP peptidesARG3
phosphorylatedrel
from MAP1ARG1
.

phosphorylate-v: volitional agent and instrument

To first address the former possibilityARGM-PRP
,
weARG0
phosphorylatedrel
PTENARG1
in vitroARGM-LOC
with CK2ARG2
and analyzed the phosphorylation by autoradiography , tryptic peptide mapping , phosphoamino acid analysis , and tandem mass spectrometry .

phosphorylation-n

ReversibleARGM-ADJ
phosphorylationrel
of proteinsARG1
is an important regulatory mechanism that occurs in both prokaryotic and eukaryotic organisms .