transactivate
transactivate.01 - stimulate the transcription of (a gene in a host cell) by binding to DNA
For Bio-AMR annotations.Aliases:
transactivate (v.)
transactivation (n.)
transactivation (n.)
Roles:
ARG0-PAG: intentional agent of transactivation (e.g. scientist)
ARG1-PPT: thing transactivated, gene
ARG2-MNR: instrument, protein, transactivator
ARG1-PPT: thing transactivated, gene
ARG2-MNR: instrument, protein, transactivator
example with agent
When
weARG0
transactivatedrel
an IE-Hoxd-4 TR geneARG1
, we found abnormalities in the neonatal skeleton similar to those induced by Hoxc-8 ( Fig . 2D ) .example with instrument
Similarly ,
pHH - luc and pAH - luc ( truncated MMTV variants containing the GRE region , both derived from a different strain of MMTV )ARG1
, were effectively transactivatedrel
with dexamethasoneARG2
.